Genome Data Science
laboratory
// BIST / Institute for Research in Biomedicine (IRB Barcelona) / Cancer Science programme / @GenomeDataLab
The most up-to-date version of our website is at:
// BIST / Institute for Research in Biomedicine (IRB Barcelona) / Cancer Science programme / @GenomeDataLab
In the GenomeDataLab, we use statistical genome analyses and machine learning methodologies for studies of massive genomic, epigenomic and transcriptomic data sets.
We aim to address outstanding questions in biology and biomedicine by insightful analysis of data originating from human tumors (somatic mutations, transcriptomes), human populations (germline variation) and metagenomes (incl. human microbiomes).
We study mechanisms of maintaining genome integrity in human cells via statistical analyses of mutation patterns in cancer. Next, we are interested in how mRNA synthesis and turnover pathways shape genomes and transcriptomes in health and disease. Finally, we combine experimental work and genomics to scan cancer genomes for driver genes and for genetic interactions to predict tumor evolution and identify novel synthetic lethalities.
read more about our research interests >>> [ 1 ] [ 2 ] [ 3 ] [ 4 ]
European Research Council ERC Starting Grant #757700 HYPER-INSIGHT "Insight into genome maintenance and cancer vulnerabilities provided by an extreme burden of somatic mutations "
Fran Supek is an EMBO Young Investigator.
Lab funding and fellowships are funded by the Severo Ochoa excellence award to the IRB Barcelona.
PI is tenured by the ICREA Research Professor program.
We are further funded by the European Union Horizon2020 program (DECIDER), the Spanish government (REPAIRSCAPE), the Catalan science agency, and the Croatian Science foundation. More information on projects >>>
"Prediction is very difficult, especially about the future." -- Niels Bohr.